CancerCalc

Clinical tools for oncology professionals

Acute Oncology

CISNE (Clinical Index of Stable febrile Neutropenia) risk tool
Used to identify patients with chemotherapy related febrile neutropenia who are low risk for medical complications.

Cytokine Release Syndrome (CRS) Grade (ASTCT criteria)
Grades severity of CRS syndrome according to the American Society for Transplantation and Cellular Therapy (ASTCT) criteria.

Immune effector Cell Associated Neurotoxicity Syndrome (ICANS) grade (ASTCT criteria)
Grades severity of ICANS according to the American Society for Transplantation and Cellular Therapy (ASTCT) criteria.

Immunotherapy toxicity management tool
Summarises management of immunotherapy toxicities according to international society guidelines

MASCC febrile neutropenia risk score
Identifies patients with febrile neutropenia who are low risk for complications and may be suitable for outpatient management.

Mirels score
Assesses risk of pathological fracture in patients with a long bone metastasis.

Spinal Instability Neoplastic Score (SINS)
Assesses spinal instability in the vertebral column in patients with neoplastic spinal disease.

Breast Oncology

CARG-BC
Predicts risk of severe chemotherapy toxicity (grade 3-5) in patients aged over 65 with early stage breast cancer.


CNS Oncology

Graded Prognostic Assessment (GPA)
Estimates survival in patients with brain metastases.

Genetics

DPYD (DPD) Activity Score Calculator (CPIC guidelines)
Provides information on functional impact of DPYD (DPD) variants and genotype guided dosing advice for fluoropyrimidine chemotherapy.

Manchester score with pathology adjustment
Predicts finding a pathogenic germline BRCA1/BRCA2 mutation in families with suspected hereditary breast or ovarian cancer.

Gastrointestinal (GI) Oncology


Gynae Oncology


Hemato-Oncology

Cytokine Release Syndrome (CRS) Grade (ASTCT criteria)
Grades severity of CRS syndrome according to the American Society for Transplantation and Cellular Therapy (ASTCT) criteria.

Early stage Hodgkin’s lymphoma risk stratification tool
Risk stratifies early stage Hodgkin’s lymphoma according to the EORTC, GHSG or NCCN criteria.

Hasenclever International Prognostic Score (IPS) for advanced stage classical Hodgkin's lymphoma
Risk stratifies advanced stage Hodgkin’s lymphoma into 6 prognostic groups.

IPI, R-IPI and NCCN-IPI scores for DLBCL
The International Prognostic Index (IPI), revised IPI (R-IPI) and NCCN-IPI are prognostic tools used to predict survival in patients with DLBCL (diffuse large B cell lymphoma).


Immune effector Cell Associated Neurotoxicity Syndrome (ICANS) grade (ASTCT criteria)
Grades severity of ICANS according to the American Society for Transplantation and Cellular Therapy (ASTCT) criteria.

Tumor Lysis Syndrome (TLS) risk assessment tool
Stratifies patients into low, intermediate or high risk for developing TLS and guides prophylaxis.


Head and Neck Oncology


Lung Oncology

Pulmonary nodule malignancy risk tools
Assess the malignancy risk of pulmonary nodules. Includes both the Herder and Brock models.

Palliative care

Opioid conversion calculator
Calculates the equi-analgesic dose of a given opioid according to desired opioid drug and route of administration.

Pharmacology

Anthracycline total exposure calculator
Calculates total anthracycline exposure based on equivalent dose of each anthracycline received.

Carboplatin dosing (Calvert formula)
Calculates the dose of carboplatin based on glomerular filtration rate and target AUC.

CARG chemotherapy toxicity calculator
Predicts risk of toxicity in older adults receiving chemotherapy.

CARG-BC
Predicts risk of severe chemotherapy toxicity (grade 3-5) in patients aged over 65 with early stage breast cancer.

Daily Chemotherapy Toxicity self Assessment Questionnaire (DCTAQ)
A patient reported outcome tool for self-reporting chemotherapy toxicities.

DPYD (DPD) Activity Score Calculator (CPIC guidelines)
Provides information on functional impact of DPYD (DPD) variants and genotype guided dosing advice for fluoropyrimidine chemotherapy.

ESMO-MCBS: ESMO Magnitude of Clinical Benefit Scale tool v1.1
Assesses the value of a new cancer therapy, taking into account the magnitude of clinical benefit, toxicity and cost within a reproducible scale.

GIST (Gastrointestinal Stromal Tumor) recurrence risk calculator
Estimates risk of recurrence in resected localised GISTs.

HFA-ICOS Cardio-Oncology Cardiovascular Risk Assessment tool
Stratifies the risk of cancer treatment related cardiovascular toxicity at baseline according to planned therapy and patient related factors.

RECIST 1.1
The RECIST criteria are used to assess radiological response to cancer therapy in solid tumours.

Surgical Oncology

Mirels score
Assesses risk of pathological fracture in patients with a long bone metastasis.

Uro-oncology