Used to identify patients with febrile neutropenia who are at risk of medical complications despite appearing clinically stable.
Use only if all criteria below apply:
- Aged ≥ 18 years
- Solid cancer receiving mild/moderate intensity chemotherapy
- Neutrophil count ≤0.5 x109/L or ≤1 and expected to decrease to ≤0.5
- Absence of organ failure (renal, cardiac, respiratory)
- Absence of hypotension (systolic≤90mmHg) or septic shock
- Absence of chronic organ insufficiency
- Absence of known severe infections
ECOG Performance Status
| 0 or 1 | 0 points |
| ≥2 | 2 points |
Hyperglycaemia? CBG≥ 6.7mmol/L or ≥13.9mmol/L if diabetic or on steroids
| No | 0 points |
| Yes | 2 points |
History of COPD? Emphysema, chronic bronchitis, decrease in forced expiratory volumes or need for oxygen therapy, corticosteroids or bronchodilators.
| No | 0 points |
| Yes | 1 points |
Cardiovascular disease? Cor pulmonale, heart failure, cardiomyopathy, hypertensive heart disease, valvular heart disease or other structural malformations. Single uncomplicated episode of AF not included here.
| No | 0 points |
| Yes | 1 points |
Mucositis grade ≥2? Presence of patchy ulcerations or pseudomembranes; or moderate pain with modified diet indicated
| No | 0 points |
| Yes | 1 points |
Monocyte count
| ≥0.2x109/L | 0 points |
| <0.2x109/L | 1 points |