CancerCalc

Clinical tools for oncology professionals


Kaplan–Meier Digitizer

This tool allows cross-trial comparisons of survival between studies.

The tool extracts data coordinates from two KM curve images to create digitized curves for each and then compares time to event between the reconstructed curves. Individual patient data (time and event status) is recreated from the extracted data coordinates.

Note: Comparisons should be considered hypothesis generating as differences in design, population and baseline characteristics between studies are not accounted.

To begin, upload an image (.png or .jpg) of the KM curve that will serve as the experimental arm of your simulated comparison. Enter the axis details in the fields below. Next digitize the curve by following the instructions below the curve. Repeat the same process for the second KM curve, which will serve as the control arm for your simulated comparison. Next move to 'Reconstruct & Analyse' tab and follow the instructions to generate the simulated KM curve.

Experimental Arm: Upload plot image, then follow instructions below image

Guidance:
  1. Click bottom-left corner (time = 0)
  2. Click bottom-right corner (max time)
  3. Click top-left corner (100% survival)
  4. Click as many points as possible on the curve of interest
More points = better accuracy!

Control Arm: Upload plot image, then follow instructions below image

Guidance:

Same steps as Experimental arm. Leave empty if no control.

Statistical Results


              

              
                
                Download IPD – Experimental Arm
              
              
                
                Download IPD – Control Arm